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Viresolve® Pro Shield H Kit Small scale devices for process development, optimization and validation studies Membrane based adsorptive prefilters to remove protein aggregates and other fouling species Nine units per kit (one membrane lot) Viresolve® Pro Modus 1.3 Device MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. Viresolve® Pro Magnus 2.2 Device MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. The Viresolve®Pro Solution provides a comprehensive, flexible template solution for viral clearance within mAb and recombinant protein bioproduction. This proven viral clearance solution delivers the highest levels of retention assurance and productivity across a broad range of feed stream characteristics. The Viresolve Pro PD kit is ideally suited for performing your evaluation, optimization and scaling studies. Each kit contains 9 Micro devices from one membrane layering combination*, a user guide and certificate of quality. Viresolve Pro Modus 1.3 Device; find Millipore-VPMD103NB1 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich.
showed that the Viresolve® Pro Shield provided more than a 20-fold increase in capacity during filtration of heavily-fouling mAbs through the Viresolve® Pro virus filtration membrane. There have also been major efforts to increase the capacity of membrane adsorbers so that they can be effectively used in bind-and-elute mode, e.g., for initial capture of monoclonal antibody products. Viresolve Pro Shield H removes protein aggregates and impurities that foul virus filters in high pH and high conductivity monoclonal antibody (mAb) feed streams. Combined with Viresolve Pro Device parvovirus retentive filters, the Viresolve Pro Shield H significantly increases processing capacity, while preserving high virus removal and high flux. Shop a large selection of products and learn more about Millipore Sigma 3P VIRESOLVE PRO MICROSHIELD KT 9 VIRESOLVE PRO MICROSHIELD . The new Viresolve ® Pro Shield H is designed for use as a prefilter with Viresolve ® Pro Devices for more robust, cost-economic viral clearance. Viresolve ® Pro Shield H removes protein aggregates and impurities that foul virus filters in high pH and high conductivity monoclonal antibody (mAb) feed streams.
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Viresolve Pro Modus 1.3 Device; find Millipore-VPMD103NB1 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. Viresolve® Pro & Pro+ Solution Magnus Holder Interactive Guide Viresolve® Pro Modus 1.3 Device - Find MSDS or SDS, a COA, data sheets and more information.
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2016-09-21 · 7 • Rely on LRV data provided by vendors • All filters demonstrate similar clearance of small viruses (18-24 nm) Pre-Filter Viral Filter Vendor Viral Filter Composition MMV LRV PPV LRV 0.1 µm PES (VPF, Shield H beta evaluated) Viresolve® Pro (Vpro) EMD Millipore PES Asymmetric Membrane 5.8 N/A4.8 5.7 0.1 µm PES Planova® 15N Asahi Kasei Bioprocess Regenerated Cellulose Hollow Fiber N/A Viresolve ® Pro Shield H removes protein aggregates and impurities that foul virus filters in high pH and high conductivity monoclonal antibody (mAb) feed streams. . Combined with Viresolve ® Pro Device parvovirus retentive filters, the Viresolve ® Pro Shield H significantly increases processing capacity, while preserving high virus removal and hi The new Viresolve® Pro Shield H is designed for use as a prefilter with Viresolve® Pro Devices for more robust, cost-economic viral clearance. Viresolve® Pro Shield H removes protein aggregates and impurities that foul virus filters in high pH and high conductivity monoclonal antibody (mAb) feed streams. β‐glucan leaching from the Viresolve Pro filter used in the purification process of mAb 5 was not expected. Results obtained in the CEX eluate of mAb 5 (<3.0–15.1 pg/mg) compared with post UF/DF measurements (0.7–1.7 pg/mg) confirm this hypothesis. Expansion of Viresolve® Pro Solution Viresolve® Pro Device + = 8 7 6 5 4 5 10 15 20 25 30 35 40 45 Conductivity (mS/cm) pH Viresolve® Pro Shield Viresolve® Pro Shield H Viresolve Pro Shield or Shield H may be optimal Figure 2.
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Each kit contains 9 Micro devices from one membrane layering combination*, a user guide and certificate of quality. The air vent prevents air locking within the device. * Viresolve Pro devices are Viresolve™ Pro Micro Device PD and Validation Kit is suited for performing filter sizing and virus validation studies. Brand: Merck Millipore VPMNVALNB9 Product Code.
Integrity Testing Integrity testing of the Viresolve Pro Micro Shield is not required. 1. Viresolve Pro Modus 1.3 Device; find Millipore-VPMD103NB1 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich.
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This robust filter configuration improves NFP filter capacity significantly reducing your overall virus filtration costs. Rapid, Reliable Composed of a PVDF material, Viresolve NFP membranes possess a unique pore structure with characteristics that enhance filtration efficiency. The new Viresolve® Pro Shield H is designed for use as a prefilter with Viresolve® Pro Devices for more robust, cost-economic viral clearance. Viresolve® Pro Shield H removes protein aggregates and impurities that foul virus filters in high pH and high conductivity monoclonal antibody (mAb) feed streams. 2016-09-21 · 7 • Rely on LRV data provided by vendors • All filters demonstrate similar clearance of small viruses (18-24 nm) Pre-Filter Viral Filter Vendor Viral Filter Composition MMV LRV PPV LRV 0.1 µm PES (VPF, Shield H beta evaluated) Viresolve® Pro (Vpro) EMD Millipore PES Asymmetric Membrane 5.8 N/A4.8 5.7 0.1 µm PES Planova® 15N Asahi Kasei Bioprocess Regenerated Cellulose Hollow Fiber N/A Expansion of Viresolve® Pro Solution Viresolve® Pro Device + = 8 7 6 5 4 5 10 15 20 25 30 35 40 45 Conductivity (mS/cm) pH Viresolve® Pro Shield Viresolve® Pro Shield H Viresolve Pro Shield or Shield H may be optimal Figure 2. The contour plot shows the optimal performance for Shield or Shield H depending on the pH and conductivity of the mAb.
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